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Rosalind
Franklin
1920 - 1958
Nearly
half a century ago, scientists raced to discover the secret of life.
At the forefront of this effort was a brilliant British researcher
who brought her substantial gifts to the study of DNA. Her name
was Rosalind Franklin.
Born into an upper middle-class Jewish family, Rosalind Franklin
was educated at a private school in London where she studied physics
and chemistry from an early age, at an advanced level, especially
so for a woman at that time. An excellent and dedicated student,
undeterred by the social standard usually set for women, she earned
a Ph.D. in physical chemistry in 1945 from Cambridge University.
She then spent four years at the Laboratoire Central des Services
Chimiques de L'Etat, in Paris. It was there that she learned
the techniques of X-ray crystallography, the scientific method that
would lead to the discovery of a lifetime.
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Photo
51
Reprinted by
permission from Nature,
Volume 171: 740-41,
©1953 Macmillan Publishers Ltd. |
Early
in her career, it was Rosalind Franklin who painstakingly conceived
of and captured "Photograph 51" of the "B" form
of DNA in 1952 while at King's College in London. It is this
photograph, acquired through 100 hours of X-ray exposure from a
machine Dr. Franklin herself refined, that revealed the structure
of DNA and the key to understanding how the blueprint of all life
on earth is passed down from generation to generation. Never before
had X-ray crystallography -- a technique of determining a molecule's
three-dimensional structure by analyzing the X-ray diffraction patterns
of crystals made up of the molecule in question -- been put
to such deft or momentous use.
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Rosalind
Franklin Looking through the Microscope
Courtesy of the American Society for Microbiology Archive
and Henry Grant/Mary Evans Picture Library. |
The
discovery of the structure of DNA was the single most important
advance of modern biology. Decoding the structure of DNA put us
on a path to understanding the human genome. Quite simply, it changed
the future of healthcare forever. James Watson and Francis Crick,
working at Cambridge University, used Photograph 51 as the basis
for their famous model of DNA.
Rosalind Franklin went on to perform exceptional research at Birkbeck
College. She died in 1958 of ovarian cancer, at age 37, perhaps
from radiation exposure from her work, or perhaps due to her own
genetic makeup. One thing is certain -- she died without ever
knowing the true magnitude of her contribution to the science of
life.
Watson
and Crick went on to win the Nobel Prize in 1962 for their DNA model -- a model that was made possible by the magnificent work of
Rosalind Franklin.
Rosalind
Franklin was one of a kind. She tirelessly blazed trails wherever
she went. Her finely honed intelligence, devotion to the highest
standards in research, thoughtful mentoring, unwavering loyalty
to friends, and deep commitment to social justice mandated for Rosalind
Franklin, a Life in Discovery.
We honor the enduring legacy of Rosalind Franklin, as well as our
own powerful aspirations, by dedicating this University to her excellence.
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